发明名称 |
SOK-1 AND METHODS OF USE |
摘要 |
A SOK polypeptide, an isolated DNA having a nucleotide sequence encoding a SOK polypeptide, and a method of determining whether a candidate compound modulates SOK-1 activity or expression, comprising the steps of providing a first and a second recombinant cell expressing a SOK gene; introducing a candidate compound into the first cell, but not into the second cell; measuring a SOK function in the first and second cells; and comparing the results obtained with the first and second SOK transformed cells, wherein an increase or decrease in the SOK function in the first cell compared to the second cell is an indication that the candidate compound modulates SOK expression or activity.
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申请公布号 |
WO9742212(A1) |
申请公布日期 |
1997.11.13 |
申请号 |
WO1997US07739 |
申请日期 |
1997.05.07 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
FORCE, THOMAS;KYRIAKIS, JOHN, M.;POMBO, CELIA, M.;BONVENTRE, JOSEPH |
分类号 |
A61K38/00;C07H21/04;C12N9/12;(IPC1-7):C07H21/04;C12N15/00;C12N1/20;C12N5/00;A61K38/51;A01N43/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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