| 摘要 |
<p>This invention provides a method of contraception which comprises administering to a female of child bearing age for 23-25 consecutive days, a first phase combination of a progestin at a daily dosage equivalent in progestational activity to 40-125 νg levonorgestrel and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 νg ethinyl estradiol for 3-8 days beginning on day 1 of the menstrual cycle, wherein the same dosage of the progestin and estrogen combination is administered in each of the 3-8 days, a second phase combination of a progestin at a daily dosage equivalent in progestational activity to 40-125 νg levonorgestrel and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 νg ethinyl estradiol, for 4-15 days beginning on the day immediately following the last day of administration of the first phase combination, wherein the same dosage of the progestin and estrogen combination is administered in each of the 4-15 days and a third phase combination of a progestin at a daily dosage equivalent in progestational activity to 40-125 νg levonorgestrel and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 νg ethinyl estradiol, for 4-15 days beginning on the day immediately following the last day of administration of the first phase combination, wherein the same dosage of the progestin and estrogen combination is administered in each of the 4-15 days provided that the daily dosage of the combination administered in the first phase is not the same as the daily dosage of the combination administered in the second phase and that the daily dosage of the combination administered in the second phase is not the same as the daily dosage of the combination administered in the third phase.</p> |
