发明名称 BISMUTH SALT OF SIALYLOLIGOSACCHARIDE AND A METHOD FOR TREATING AND INHIBITING GASTRIC AND DUODENAL ULCERS WITH SAME
摘要 <p>A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising a bismuth salt of an oligosaccharide of formula (I): (NeuAc-α(2-3)-pGal-β(1)-(-X-)m-(-Y-)n-)p-Z, wherein X = a chemical bond or a group capable of linking the p galactose to either the linking group Y or the multivalent support Z; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C; Y = a linking group; Z = a multivalent support; m = 0 or 1; n = 0 or 1; and p = an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising a bismuth salt of an oligosaccharide of formula (III): NeuAc-α(2-3)-pGal-β(1)-A, wherein A = a group capable of bonding to the p galactose; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C.</p>
申请公布号 WO1997041875(A1) 申请公布日期 1997.11.13
申请号 US1997006376 申请日期 1997.04.28
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