SYSTEME UND METHODEN ZUR ANSAMMLUNG VON PLÄTTCHEN MIT VERBESSERTER AUSBEUTE

摘要

A centrifugal separation apparatus for separating whole blood into red blood cells and a plasma constituent carrying platelets is described. The apparatus comprises a separation chamber (10, 31A, 58) which has first and second spaced apart walls (16, 18, 64, 66) that form a separation zone (84) having a low-G side and a high-G side that is located radially further from the rotational axis than the low-G side. The separation zone includes an entry region (122) where the whole blood enters the separation chamber to begin separation into red blood cells toward the high-G side and the plasma constituent toward the low-G side. Inlet and outlet openings (20, 68, 24, 72) are provided that communicate with the separation chamber. The inlet opening provides for the introduction of whole blood into the entry region. The outlet opening (24, 72) directs the plasma constituent from a plasma constituent collection region (124) at the low-G side of the separation zone adjacent the entry region while whole blood is introduced into the entry region through the inlet opening. The apparatus also comprises an interface control system (134) that is located outside the separation chamber and is arranged to monitor the location of an interface (26) that forms between the red blood cells and the plasma constituent during separation by viewing into the separation zone. A method for centrifugally separating whole blood into red blood cells and a plasma constituent carrying platelets is also described.