Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements

摘要

A dry immunoassay analytical element for assaying a ligand, comprising a support bearing: 1. an enzyme labeled ligand or an enzyme labeled receptor zone; 2. a spreading zone; and 3. a receptor zone containing a fixed concentration of an immobilized receptor for the ligand and the labeled ligand when present and the receptor is covalently bonded to polymeric beads having a diameter in the range of 0.1 to 5 mu m; characterized in that the element contains a diaryl telluride (DAT) compound and the zones can be in the same or separate layers.