| 发明名称 |
Oxadiazoles useful in the treatment of senile dementia |
| 摘要 |
A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring, and substituted on the other ring carbon atom with a substituent of low lipophilicity; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses.
|
| 申请公布号 |
US5686463(A) |
申请公布日期 |
1997.11.11 |
| 申请号 |
US19870027989 |
申请日期 |
1987.03.19 |
| 申请人 |
MERCK, SHARP & DOHME, LTD. |
发明人 |
BAKER, RAYMOND;MERCHANT, KEVIN JOHN;MACLEOD, ANGUS MURRAY;SAUNDERS, JOHN |
| 分类号 |
A61K31/435;A61K31/41;A61K31/55;A61P25/00;A61P25/04;A61P25/18;A61P25/28;A61P29/00;A61P43/00;C07D209/52;C07D413/04;C07D451/02;C07D453/02;C07D453/06;C07D471/08;C07D487/04;C07D487/08;(IPC1-7):A61K31/41 |
主分类号 |
A61K31/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
