| 发明名称 |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE) |
| 摘要 |
This invention discloses high-affinity oligonucleotide ligands to human Immunoglobulin E (IgE), specifically RNA and ssDNA ligands having the ability to bind to IgE, and the methods for obtaining such ligands. The ligands are capable of inhibiting the interaction of IgE with its receptor.
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| 申请公布号 |
US5686592(A) |
申请公布日期 |
1997.11.11 |
| 申请号 |
US19950471985 |
申请日期 |
1995.06.06 |
| 申请人 |
NEXSTAR PHARMACEUTICALS, INC. |
发明人 |
WIEGAND, TORSTEN WALTER;TASSET, DIANE;GOLD, LARRY |
| 分类号 |
C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K14/00;C12N9/12;C12N15/10;C12N15/115;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):C07H21/04;C07H21/02;C12P19/34 |
主分类号 |
C07B61/00 |
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