发明名称 COMBINED USE OF GnRH AGONIST AND ANTAGONIST
摘要 <p>The present invention relates to a pharmaceutical comprising a luteinizing hormone releasing hormone agonist in combination with a luteinizing hormone releasing hormone antagonist. By using a luteinizing hormone releasing hormone agonist and a luteinizing hormone releasing hormone antagonist in combination, the transient exacerbation with elevation of serum testosterone and estrogen owing to the pituitary-gonadotropic action (acute action) manifested immediately following an initial dose of the luteinizing hormone releasing hormone agonist can be successfully obviated.</p>
申请公布号 WO1997040846(A1) 申请公布日期 1997.11.06
申请号 JP1997001459 申请日期 1997.04.25
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