发明名称 |
Improved mutants of (2,5-DKG) reductase |
摘要 |
Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce 2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the following characteristics: improved temperature stability, increased resistance to substrate inhibition, increased turnover of the substrate by the enzyme and increased affinity for the substrate. |
申请公布号 |
WO9725432(A3) |
申请公布日期 |
1997.11.06 |
申请号 |
WO1997US00097 |
申请日期 |
1997.01.09 |
申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;POWERS, DAVID, B.;ANDERSON, STEPHEN |
发明人 |
POWERS, DAVID, B.;ANDERSON, STEPHEN |
分类号 |
C12N15/09;C12N1/21;C12N9/04;C12N15/53 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|