There is disclosed a purified multimerase having an indirect and a direct proteolytic activity, which converts vWF having a singlet structure to vWF having a satellite structure and is active in the presence of the serine protease inhibitor DFP or the calpain protease inhibitor Z-Leu-Leu-Tyr-CHN2, as well as a method of preparing the multimerase according to the invention.
申请公布号
WO9741206(A2)
申请公布日期
1997.11.06
申请号
WO1997EP02131
申请日期
1997.04.25
申请人
IMMUNO AKTIENGESELLSCHAFT
发明人
FURLAN, MIHA;LAEMMLE, BERNHARD;SCHWARZ, HANS-PETER;TURECEK, PETER;EIBL, JOHANN