发明名称 |
Ubiquitin-specific proteases |
摘要 |
The disclosure relates to a generic class of ubiquitin-specific proteases which specifically cleave at the C-terminus of the ubiquitin moiety in a ubiquitin fusion protein irrespective of the size of the ubiquitin fusion protein. More specifically, the disclosure relates to ubiquitin-specific proteases of this class which have been isolated from a cell. The disclosure also relates to isolated DNA sequences encoding the proteases of this class.
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申请公布号 |
US5683904(A) |
申请公布日期 |
1997.11.04 |
申请号 |
US19950487203 |
申请日期 |
1995.06.07 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
BAKER, ROHAN T.;TOBIAS, JOHN W.;VARSHAVSKY, ALEXANDER |
分类号 |
C12N15/09;C07K14/00;C12N1/21;C12N9/52;C12N9/60;C12N15/57;C12N15/62;C12P21/06;C12R1/19;(IPC1-7):C12N1/20;C12N9/50;C12N9/48;C12N1/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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