The present invention relates to new and useful nucleoside thiophosphoroamidites and polynucleotide phosphorodithioate compounds as well as the processes whereby these compounds may be used for synthesizing new mononucleotides and polynucleotides having phosphorothioate and phosphorodithioate internucleotide linkages.
申请公布号
US5684148(A)
申请公布日期
1997.11.04
申请号
US19950442705
申请日期
1995.05.17
申请人
COMPETITIVE TECHNOLOGIES, INC.
发明人
CARUTHERS, MARVIN H.;BRILL, WOLFGANG K. D.;YAU, ERIC;MA, MICHAEL;NIELSEN, JOHN