摘要 |
Novel tricyclic triazolo derivatives and pharmaceutically acceptable salts thereof, which are useful as anti-inflammation agents, anti-allergy agents or anti-PAF agents as well as processes for producing the same are disclosed. The triazolo derivatives of the present invention are represented by the formula (I): <IMAGE> (I) [wherein R1 represents hydrogen, lower alkyl or C3-C5 cycloalkyl; R2 and R3 respectively represent hydrogen, lower alkyl, lower alkoxy or halogen; W represents C=O or CR4R5 (wherein R4 and R5 respectively represents hydrogen or lower alkyl); A represents C1-C5 straight or branched saturated or unsaturated alkylene which may contain one or more hetero atoms; l represents 0 to 2, n represents 1 to 3, . . . represents single bond or double bond; Y represents N or C; Z represents C(B)Ar1Ar2 (wherein B represents hydrogen, hydroxy or methoxy, Ar1 and Ar2 respectively represent hydrogen or substituted or non-substituted aryl), CAr1Ar2 (wherein Ar1 and Ar2 represent the same meanings as mentioned above), O-CHAr1Ar2 (wherein Ar1 and Ar2 represent the same meanings as mentioned above) or condensed aromatic ring].
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