发明名称 |
Treatment of human viral infections |
摘要 |
Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir and AZT and 2-amino-9-(2-hydroxyethoxymethyl)purine or an ester thereof.
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申请公布号 |
US5683990(A) |
申请公布日期 |
1997.11.04 |
申请号 |
US19860899079 |
申请日期 |
1986.08.21 |
申请人 |
GLAXO WELLCOME INC. |
发明人 |
RIDEOUT, JANET LITSTER;BARRY, DAVID WALTER;LEHRMAN, SANDRA NUSINOFF;ST. CLAIR, MARTHA HEIDER;FURMAN, PHILLIP ALLEN |
分类号 |
A01N43/04;A01N43/90;A61K38/21;C07H19/06;C07H19/10;C07H19/16;(IPC1-7):A61K31/705;A61K31/52 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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