| 发明名称 |
IMPROVED SYNTHESIS OF CYCLOPROPYLACETYLENE. |
| 摘要 |
<p>Cyclopropylacetylene is prepared by mixing a strong base and 5-halo-1-pentyne in an aprotic solvent; the temperature is allowed to rise from 0 to 150 degree C and this temperature is maintained for at least 15 minutes. The reaction mixture is then quenched with a proton source.</p> |
| 申请公布号 |
MX9705562(A) |
申请公布日期 |
1997.10.31 |
| 申请号 |
MX19970005562 |
申请日期 |
1996.01.19 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ANDREW S. THOMPSON;EDWARD G. CORLEY;MARTHA HUNTINGTON |
| 分类号 |
C07D265/18;A61K31/535;A61P31/12;C07C1/30;C07C13/04;(IPC1-7):C07C13/04;C07C01/30 |
主分类号 |
C07D265/18 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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