| 发明名称 |
PHARMACEUTICAL COMPOSITIONS. |
| 摘要 |
<p>This invention provides a microemulsion pre-concentrate comprising a difficultly soluble active agent and a carrier medium comprising: 1) a hydrophilic phase which comprises dimethylisosorbide and/or a lower alkyl alkanoic ester, 2) a lipophilic phase, and 3) a surfactant. The active agent may be a cyclosporin or a macrolide. In another aspect, this invention provides a pharmaceutical composition for enteral or parenteral administration comprising a macrolide and an acid.</p> |
| 申请公布号 |
MX9702701(A) |
申请公布日期 |
1997.10.31 |
| 申请号 |
MX19970002701 |
申请日期 |
1995.10.25 |
| 申请人 |
NOVARTIS AG. |
发明人 |
SYLVAIN COTTENS;BARBARA HAEBERLIN;RICHARD SEDRANI;JACKY VONDERSCHER |
| 分类号 |
A61K47/22;A61K;A61K9/00;A61K9/107;A61K9/48;A61K31/395;A61K31/435;A61K31/436;A61K38/00;A61K38/12;A61K38/13;A61K47/12;A61K47/14;A61P29/00;A61P31/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;(IPC1-7):A61K38/18;A61K09/107;A61K09/48 |
主分类号 |
A61K47/22 |
| 代理机构 |
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代理人 |
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| 主权项 |
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