| 摘要 |
Compounds of general formula (I) and salts thereof, giving quinolone derivatives which exhibit high antibacterial activity against various bacteria including resistant ones and high safety, wherein R1 is cycloalkyl; R2 is hydrogen, amino, hydroxyl, mercapto, halogenomethyl, alkyl, alkenyl, alkynyl or alkoxy; R3 is amino, halogenomethyl, halogenomethoxy, alkyl, alkenyl, alkynyl or alkoxy; R4 is hydrogen or C1-C6 alkyl; R5 is C3-C6 cycloalkyl; and X is halogeno or hydrogen, with the proviso that these substituents may be further substituted; and Y is hydrogen, phenyl, acetoxymethyl, pivaloyloxymethyl, ethoxycarbonyl, choline, dimethylaminoethyl, 5-indanyl, phthalidinyl, 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl, 3-acetoxy-2-oxobutyl, C1-C6 alkyl, C2-C7 alkoxymethyl or phenylalkyl composed of C1-C6 alkylene and phenyl.
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