Monoclonal antibodies that inhibit growth of kaposi's sarcoma
摘要
<p>The present invention involves the use of monoclonal antibodies specific for Oncostatin M to inhibit the growth potentiating effect of Oncostatin M on Kaposi's Sarcoma associated with AIDS. In particular neutralizing anti-Oncostatin M antibodies inhibit the growth of Kaposi's Sarcoma which is potentiated and maintained by Oncostatin M or a factor found in conditioned media of an HTLV-II transformed T cell line.</p>
申请公布号
GR3024336(T3)
申请公布日期
1997.10.31
申请号
GR19970401981T
申请日期
1997.07.31
申请人
ONCOGEN LIMITED PARTNERSHIP;UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人
SALAHUDDIN, SYED ZAKI;NAKAMURA, SHUJI;GALLO, ROBERT C.;RADKA, SUSAN F.;LINSLEY, PETER S.;SHOYAB, MOHAMMED