发明名称 Pharmaceutical agents that contain perfluoroalkyl-containing metal complexes and their use in tumor therapy and interventional radiology.
摘要 The invention relates to pharmaceutical agents containing perfluoroalkylated metal complexes of the general formula (I) RF-L-A and the use thereof in tumour therapy and interventional radiology, in which formula RF is a perfluorinated, straight-chain or branched carbon chain with the formula -CnF2nX, in which X is a terminal fluorine, chlorine, bromine, iodine or hydrogen atom and n represents the numbers 4-30, L is a binding group, and A is a metal complex or the salts thereof of organic and/or inorganic bases or amino acids or amino acid amides. L and A are defined in detail in the description.
申请公布号 ZA9701537(B) 申请公布日期 1997.10.30
申请号 ZA19970001537 申请日期 1997.02.21
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 JOHANNES PLATZEK;BERND RADUECHEL;HANNS-JOACHIM WEINMANN;ULRICH NIEDBALLA;WOLFGANG SCHLECKER;THOMAS FRENZEL
分类号 A61K31/28;A61K31/555;A61K33/24;A61K45/06;A61K49/06;C07D257/02;C07D295/26 主分类号 A61K31/28
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