A PROKARYOTIC PROTEIN HAVING FUNCTIONAL AND STRUCTURAL HOMOLOGY WITH THE HUMAN P-GLYCOPROTEIN ENCODED BY THE MDR-1 GENE, NUCLEIC ACIDS ENCODING AND CELLS EXPRESSING SAID PROTEIN
摘要
The present invention relates to protein and genes encoding said protein as well as cells harbouring said genes or protein. The protein is a prokaryotic homolog of the human P-glycoprotein which is encoded by the MDR-1 gene. The MDR-1 gene is a gene related to the occurrence of multidrug resistance.
申请公布号
WO9740160(A1)
申请公布日期
1997.10.30
申请号
WO1997NL00216
申请日期
1997.04.24
申请人
RIJKSUNIVERSITEIT TE GRONINGEN;VAN VEEN, HENDRIK, WILLEM;VENEMA, KONRAAD;BOLHUIS, HENDRIK;KONINGS, WILHELMUS, NICOLAAS
发明人
VAN VEEN, HENDRIK, WILLEM;VENEMA, KONRAAD;BOLHUIS, HENDRIK;KONINGS, WILHELMUS, NICOLAAS