PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES

摘要

A process for producing pyrrolidine derivatives represented by general formula (2) or salts thereof in a simple and economical manner with a good productivity in a high yield. The process comprises conducting hydrogenolysis of a compound represented by general formula (1) with a metallic catalyst in the presence of at least one protonic acid selected from the group consisting of hydrochloric acid, sulfuric acid, phosphoric acid, p-toluenesulfonic acid, methanesulfonic acid, acetic acid, n-butyric acid, trifluoroacetic acid, and citric acid, wherein R represents a 1-cyano-1,1-diphenylmethyl, 1-carbamoyl-1,1-diphenylmethyl, n-butyryloxy, methanesulfonyloxy, or p-toluenesulfonyloxy group.