发明名称 ORAL DOSAGE-FORMS CONTAINING A 'beta'-LACTAM ANTIBIOTIC.
摘要 <p>A granulate, containing at least 50 wt.percent of a water soluble 'beta'-lactam antibiotic, is provided. A process to prepare a granulate containing such 'beta'-lactam antibiotic comprises moistening components making up the granulate with an aqueous solution containing no substantial amount of a wet granulation binding agent. Oral dosage-forms, which contain the said antibiotic in a granular form, a cellulose product and a disintegrant and which quickly disperse when placed in an aqueous environment, are disclosed, as well as a method for the preparation of the dosage-forms.</p>
申请公布号 MX9706062(A) 申请公布日期 1997.10.31
申请号 MX19970006062 申请日期 1996.02.08
申请人 YAMANOUCHI EUROPE B.V. 发明人 ROBERTUS CORNELIS VAN KOUTRIK;GERRIT JAN SIJBRANDS
分类号 A61K9/00;A61K9/16;A61K31/43;A61K31/431;A61K31/545;(IPC1-7):A61K09/16 主分类号 A61K9/00
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