PROPAGYLGLYCINE DERIVATIVES, PREPARATION AND UTILISATION THEREOF AS SYNTHESIS INTERMEDIATES

摘要

Compounds of formula (I) wherein R2 is -CH2C=CH or -CH2C=C-Het where Het is a 2-aminopyridyl, 2-aminopyrimidyl, 6-aminopyridazinyl, imidazol-4-yl group, R3 and R4 each represent hydrogen, (C1-C4)alkyl, (C1-C4)alkoxycarbonyl, ArCH2CO2- or ArSO2- where Ar is an aryl group, or a group (a) where R7 is hydrogen or -COR, R being straight or branched (C1-C7) alkyl, -(CH2)nOCH3 or -CH2O(C2H4O)nCH3 (n is 1, 2 or 3) and A is chosen among the phenyl, pyrimidyl, pyridinyl, thienyl, thiazolyl and furyl groups, R6 represents either a straight or branched (C1-C4) alkoxy group, or a benzyloxy group or a group (b) where R12 is a hydrogen atom or a carboxylic or (C1-C4)alkoxycarbonyl group and R13 is a straight or branched (C1-C4)alkyl group. They constitute synthesis intermediates.