Diagnosis and monitoring of neurological disease

摘要

The invention provides a method for diagnosis or prediction of relapse or monitoring of disease activity in a patient with neurological disease, particularly multiple sclerosis, comprising quantifying the amount of MMP-9, fragments thereof or allelic variants thereof, and/or a tissue inhibitor of metalloproteinase (TIMP), fragments thereof or allelic variants thereof, present in the blood of a patient, and comparing that amount with a control.