发明名称 |
Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
摘要 |
A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.
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申请公布号 |
US5681585(A) |
申请公布日期 |
1997.10.28 |
申请号 |
US19960667052 |
申请日期 |
1996.06.20 |
申请人 |
EURO-CELTIQUE, S.A. |
发明人 |
OSHLACK, BENJAMIN;CHASIN, MARK;PEDI, JR., FRANK |
分类号 |
A61K9/16;A61K9/20;A61K9/28;A61K9/50;A61K9/52;A61K31/485;A61K31/522;(IPC1-7):A61K9/62 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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