发明名称 |
Trifunctional antithrombin and antiplatelet peptides |
摘要 |
Novel compounds which contain a thrombin catalytic-site inhibitor coupled with an anion binding exosite associating moiety via an RGD-X bridging sequence are trifunctional anticoagulants useful in treating venous or arterial thrombotic conditions.
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申请公布号 |
US5681925(A) |
申请公布日期 |
1997.10.28 |
申请号 |
US19950502989 |
申请日期 |
1995.07.17 |
申请人 |
MERRELL PHARMACEUTICALS INC. |
发明人 |
BROERSMA, JR., ROBERT J.;OWEN, THOMAS J.;KRSTENANSKY, JOHN L. |
分类号 |
A61K38/00;A61K38/46;A61K38/55;A61P7/02;C07K5/08;C07K7/00;C07K14/745;C07K14/75;C07K14/815;(IPC1-7):A61K38/36;A61K38/16;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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