EMULSIONS OF PERFLUORO COMPOUNDS AS SOLVENTS FOR NITRIC OXIDE (NO)

摘要

The present invention involves perfluoro compound emulsions including nitric oxide, their preparation and their use. These emulsions provide a new source of nitric oxide. Such nitric oxide-containing emulsions maybe used for the administration of nitric oxide to individuals in need thereof. Individuals in need of nitric oxide administration can include those suffering from hypertension, preeclampsia and a number of other situations where an increased blood flow, for example, is desirable. In addition, given the long use of perfluoro compound emulsions as blood substitutes, the present invention provides a relatively safe mode for administering and distributing nitric oxide, (see Figure 1) - without potential negative side effects such as toxicities due to drug metabolites.