| 发明名称 |
FLUORINATED XANTHENE DERIVATIVES |
| 摘要 |
The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess greater photostability and have lower sensitivity to pH changes in the physiological range of 6-8 than do non-fluorinated dyes, exhibit less quenching when conjugated to a substance, and possess additional advantages. The dyes of the invention are useful as detectable tracers and for preparing conjugates of organic and inorganic substances. |
| 申请公布号 |
WO9739064(A1) |
申请公布日期 |
1997.10.23 |
| 申请号 |
WO1997US06090 |
申请日期 |
1997.04.11 |
| 申请人 |
MOLECULAR PROBES, INC. |
发明人 |
GEE, KYLE, R.;POOT, MARTIN;KLAUBERT, DIETER, H.;SUN, WEI-CHUAN;HAUGLAND, RICHARD, P.;MAO, FEI |
| 分类号 |
G01N33/48;C07B61/00;C07C37/00;C07C37/055;C07C39/27;C07C205/26;C07C205/37;C07C209/36;C07C213/00;C07C217/82;C07C245/20;C07D311/82;C07D493/10;C07F9/6561;C07K1/13;C07K16/18;C09B11/00;C09B11/24;C09B11/28;G01N1/30;G01N21/76;(IPC1-7):C09B11/00 |
主分类号 |
G01N33/48 |
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