| 摘要 |
<p>The present invention relates to a method of treating cancer which comprises administering to a mammalian patient an effective amount of a combination of geranylgeranyl-protein transferase-type I inhibitor and a farnesyl protein transferase inhibitor. The invention further relates to a method of treating cancer which comprises administering to a mammalian patient an effective amount of a combination of a selective geranylgeranyl-protein transferase-type I inhibitor and a selective farnesyl protein transferase inhibitor. The figure shows the autoradiograph of the immunoprecipates from assay set No. 1 of the in vivo prenylation inhibition by a combination by a selective of FPTase inhibitor and a selective geranylgeranyl-protein transferase-type I inhibitor.</p> |
