发明名称 Verfahren zur Gewinnung und Anwendung eines biologisch aktiven Eiweisstoffes - Kollagenfragment HF-COLL-18/514cf - in partiell aufgereinigter und synthetischer Form aus Körperflüssigkeiten zur Beeinflussung des Zellwachstums und der Diagnose von Kollagenerkrankungen sowie der Osteoporose
摘要 The invention relates to a peptide from human blood, HF-COLL-18/514cf. For the purpose of diagnostic, medical and commercial use as a drug, the structure of said peptide has been identified. Isolation of said novel peptide, HF-COLL-18/514cf, proves the existence of HF-COLL-18/514cf. The molecular form of HF-COLL-18/514cf has been revealed by mass spectrometry and amino-terminal sequencing, and the fact that HF-COLL-18/514cf is a natural peptide which should be used to treat numerous diseases related to cell growth disorders, in particular of endothelial cells and vessels, and for example in cancer. HF-COLL-18/514cf can also be used commercially in a pure form or as a natural raw extract when researching new cell functions.
申请公布号 DE19615710(A1) 申请公布日期 1997.10.23
申请号 DE19961015710 申请日期 1996.04.22
申请人 FORSSMANN, WOLF-GEORG, PROF. DR.MED.DR.H.C., 30625 HANNOVER, DE 发明人 SCHRADER, MICHAEL, DR.RER.NAT., 30625 HANNOVER, DE;FORSSMANN, WOLF-GEORG, PROF. DR.MED., 30625 HANNOVER, DE;RAIDA, MANFRED, DR.PHIL.NAT., 30625 HANNOVER, DE;SCHULZ-KNAPPE, PETER, DR.MED., 30625 HANNOVER, DE
分类号 C12N15/09;A61K9/12;A61K31/00;A61K38/00;A61K39/395;A61K45/00;A61P29/00;A61P35/00;A61P37/00;C07K14/78;C07K16/18;C12P21/08;G01N33/53;G01N33/577;(IPC1-7):C07K14/78;A61K38/39;C07K1/16 主分类号 C12N15/09
代理机构 代理人
主权项
地址