Nachweis numerischer Veränderungen in der DNA von Zellen

摘要

The invention pertains to a process for identifying numerical changes in cell DNA, comprising the following steps: (a) isolate DNA from normal cells and amplify the DNA by means of a polymerase chain reaction using tag primers; (b) in situ hybridize the cells under study with the amplified DNA; (c) amplify DNA from the in situ hybridized cells from (b) by means of a polymerase chain reaction using the tag primers from (a), and (d) identify numerical changes in the amplified DNA from (c) in a normal way. The invention also pertains to a kit suitable for carrying out the process.