发明名称 |
HYDROLYZED CELLULOSE GRANULATIONS FOR PHARMACEUTICALS |
摘要 |
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97 % by weight pharmaceutical active, from about 3 to 99 % by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
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申请公布号 |
CA2252394(A1) |
申请公布日期 |
1997.10.23 |
申请号 |
CA19972252394 |
申请日期 |
1997.04.15 |
申请人 |
FMC CORPORATION |
发明人 |
ERKOBONI, DAVID F.;VALDYKA, RONALD S., JR.;KARETNY, MARC S.;STAMATO, HOWARD J. |
分类号 |
A61K9/16;A61K9/20;(IPC1-7):A61K9/16;A61K31/135;A61K31/19;A61K47/38 |
主分类号 |
A61K9/16 |
代理机构 |
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