发明名称 |
ACRIDONE-DERIVED COMPOUNDS USEFUL AS ANTINEOPLASTIC AND ANTIRETROVIRAL AGENTS |
摘要 |
The present invention relates to several novel acridone-derived compounds of formula (I) or (II). These compounds are potent anti-viral agents, useful in the treatment of viral diseases, such as Human Immunodeficiency Virus. In addition, these compounds are anti-neoplastic agents useful in the treatment of various forms of cancer. In said formula (I) or (II) R1 and R2 are independently -H, -OH, amino, alkylamino, dialkylamino, alkoxy, alkyl, haloalkyl or halogen; n is 2 to 6, X and X' are independently -N or -NO2; Y and Y' are independently -N or -CH, or -H; and the double-slash represents a double bond or no bond.
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申请公布号 |
WO9738999(A1) |
申请公布日期 |
1997.10.23 |
申请号 |
WO1997US07070 |
申请日期 |
1997.04.09 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, RE;MICHEJDA, CHRISTOPHER, J.;CHOLODY, MAREK, W.;RICE, WILLIAM, G.;TURPIN, JAMES, A. |
发明人 |
MICHEJDA, CHRISTOPHER, J.;CHOLODY, MAREK, W.;RICE, WILLIAM, G.;TURPIN, JAMES, A. |
分类号 |
C07D219/06;A61K31/00;A61K31/435;A61K31/4353;A61K31/437;A61K31/47;A61K31/473;A61P31/00;A61P31/12;A61P31/18;A61P35/00;C07D471/06;C07D519/00;(IPC1-7):C07D471/06 |
主分类号 |
C07D219/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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