发明名称 |
Inhibitors of farnesyl-protein transferase |
摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras. |
申请公布号 |
AU2730797(A) |
申请公布日期 |
1997.10.22 |
申请号 |
AU19970027307 |
申请日期 |
1997.04.01 |
申请人 |
MERCK & CO., INC. |
发明人 |
NEVILLE J ANTHONY |
分类号 |
A61K31/00;A61K31/415;A61K31/4164;A61K31/4178;A61K31/425;A61K31/427;A61P9/00;A61P13/00;A61P13/12;A61P27/00;A61P27/02;A61P31/00;A61P31/12;A61P35/00;A61P43/00;C07D233/54;C07D233/70;C07D401/14;C07D403/10;C07D403/14;C07D409/10;C07D409/14;C07D413/06;C07D417/06;C07D417/14 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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