发明名称 Unbridged bis-aryl carbinol derivatives, compositions and methods of use
摘要 PCT No. PCT/US93/02289 Sec. 371 Date Sep. 26, 1994 Sec. 102(e) Date Sep. 26, 1994 PCT Filed Mar. 22, 1993 PCT Pub. No. WO93/20063 PCT Pub. Date Oct. 14, 1993Disclosed is a compound of Formula 1.0: <IMAGE> (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein: AR1 represents <IMAGE> AR2 represents <IMAGE> or a five-membered heterocyclic aromatic group selected from the group consisting of Formulas I to XII, wherein the substitutable carbon atoms of the five-membered heterocyclic group can optionally be substituted with a group R1. Also disclosed are pharmaceutical compositions containing compounds of Formula 1.0. Further disclosed is a method for treating asthma, allergy and inflammation by administering an anti-asthmatic, anti-allergic or anti-inflammatory, respectively, effective amount of a compound of Formula 1.0.
申请公布号 US5679692(A) 申请公布日期 1997.10.21
申请号 US19940307801 申请日期 1994.09.26
申请人 SCHERING CORPORATION 发明人 FRIARY, RICHARD;PIWINSKI, JOHN J.;WONG, JESSE K.
分类号 A61K31/4427;A61K31/4433;A61K31/445;A61P11/00;A61P37/08;C07D401/06;C07D401/14;C07D409/14;C07D417/14;(IPC1-7):A61K31/445;C07D401/12 主分类号 A61K31/4427
代理机构 代理人
主权项
地址