Pharmaceutical formulation comprised of polymyxintrimethoprim and an anti-inflammatory drug for ophthalmic and otic topical use

摘要

It comprises: 0.005-1.0% of trimethoprim or a pharmaceutically acceptable salt thereof: 0.01-0.3% of polymyxin or a pharmaceutically acceptable salt thereof: 0.001-5% of a steroidal or non-steroidal anti-inflammatory drug and, optionally, one or more ingredients selected from among isotonizing agents, pH buffers, viscosity modifying agents, wetting agents, chelating agents, anti-oxidants, preservatives and vehicles. The formulation has a pH between 4 and 8.5. It is applicable in the treatment of ophthalmic and otic infections accompanied by inflammation.