DRUG FOR THE TREATMENT OF TUMOURS

摘要

The invention concerns a drug containing as its active constituent a substance which inhibits the action of TGF.beta. on tumour cells of epithelial origin for the treatment of epithelial, invasive tumours characterized by a reversible transition of the cells from an epithelial, non-invasive state to a fibroblastic, invasive state. The drug contains a TGF.beta. inhibitor, preferably in combination with a Ras inhibitor. The invention also concerns a method of screening substances for the treatment of epithelial, invasive tumours.