NEW QUINAZOLINE-4-AMINO-2-(PIPERIDINE-1-YL-4-SUBSTITUTED) DERIVATIVES HAVING ANTI-HYPERTENSIVE ACTIVITY, A METHOD FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE

摘要

New quinazolines are described having anti-hypertensive activity of general formula (I), in which Ar is : an unsubstituted phenyl group or a phenyl group mono-substituted with a methoxy, ethoxy or methyl group ; an unsubstituted pyridyl group (2-, 3- or 4-yl) or a pyridyl group mono-substituted with a methoxy or methyl group ; an unsubstituted furyl group (2- or 3-yl) or a furyl group substituted with a methoxy or methyl group ; a benzofuryl group (2- or 3yl) ; an indolyl group (2- or 3-yl) ; a thiophenyl group (2- or 3-yl) ; a naphthyl group (1- or 2-yl) and their salts obtained from pharmaceutically acceptable inorganic or organic acids.