发明名称 |
A PROCESS FOR PURIFICATION OF K-252A |
摘要 |
A method of purifying K-252a characterized by treating microbial cells containing K-252a represented by formula (I) with an alkali solution to thereby convert the K-252a to K-252b represented by formula (II) or an alkali salt thereof to cause the same to be leached outside the microbial cells, methylating the K-252b or alkali salt thus leached to reconvert the same to K252a, and isolating and recovering the K-252a.
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申请公布号 |
CA2228471(A1) |
申请公布日期 |
1997.10.16 |
申请号 |
CA19972228471 |
申请日期 |
1997.04.02 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
KINOSHITA, TADASHI;KINO, MITSUTAKA;NAGAMURA, SATORU |
分类号 |
C07D498/22;C12P17/18;(IPC1-7):C07D498/22 |
主分类号 |
C07D498/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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