摘要 |
<p>A process for encapsulation of caplets in a capsule comprises the following steps: a) providing empty capsule parts; b) filling at least one of said capsule parts with one or more caplets; c) putting said capsule parts together; and d) treating the combined parts by cold shrinking. The solid dosage forms obtainable by such a process are tamper-proof in that they cannot be opened in a way to be reassembled without showing such opening process.</p> |