发明名称 |
ANTICACHECTIC COMPOSITION |
摘要 |
A medicinal composition for the prophylaxis and treatment of cachexia which comprises a compound of formula (I) wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula -CO-, -CH(OH)-, or -NR<3>- (R<3> represents an alkyl group that may be substituted); m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulphur; R<1> represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R<1>; L and M respectively represent hydrogen or may be combined with each other to form a bond, provided that when m and n are O, X represents CH, A represents a bond, Q represents sulfur, R<1>, L and M respectively represent hydrogen, and ring E does not have further substituents, R does not represent dihydrobenzopyranyl; or a salt thereof.
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申请公布号 |
WO9737656(A1) |
申请公布日期 |
1997.10.16 |
申请号 |
WO1997JP01148 |
申请日期 |
1997.04.03 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;MOMOSE, YU;MATSUTANI, ETSUYA;SOHDA, TAKASHI |
发明人 |
MOMOSE, YU;MATSUTANI, ETSUYA;SOHDA, TAKASHI |
分类号 |
C07D277/20;A61K31/42;A61K31/421;A61K31/422;A61K31/425;A61K31/426;A61K31/427;A61K31/44;A61K31/4439;A61P3/00;A61P3/08;A61P3/10;A61P43/00;C07D263/44;C07D277/34;C07D413/06;C07D413/14;C07D417/06;C07D417/12;C07D417/14;(IPC1-7):A61K31/42 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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