发明名称 CYTOMODULATING CONJUGATES OF MEMBERS OF SPECIFIC BINDING PAIRS
摘要 Novel conjugates are provided comprising a moiety capable of specifically binding to a target cell joined to a selective moiety for binding to an endogenous effector agent, capable of causing cell inactivation or cytotoxicity. Example of conjugates are a ligand for a surface membrane protein, e.g. IL-2 receptor, joined to an alpha -galactosyl epitope, or a polysaccharide A or B antigen. The conjugates may be used to specifically destroy cells associated with a pathogenic condition.
申请公布号 WO9737690(A2) 申请公布日期 1997.10.16
申请号 WO1997US05842 申请日期 1997.04.09
申请人 SANGSTAT MEDICAL CORPORATION 发明人 POULETTY, PHILIPPE
分类号 A61K38/20;A61K47/48 主分类号 A61K38/20
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