摘要 |
Novel conjugates are provided comprising a moiety capable of specifically binding to a target cell joined to a selective moiety for binding to an endogenous effector agent, capable of causing cell inactivation or cytotoxicity. Example of conjugates are a ligand for a surface membrane protein, e.g. IL-2 receptor, joined to an alpha -galactosyl epitope, or a polysaccharide A or B antigen. The conjugates may be used to specifically destroy cells associated with a pathogenic condition. |