1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME

摘要

A 1,4-dihydropyridine compound having the formula (I): <CHEM> wherein, R<1> indicates -COO-A-(3-pyridyl), A indicates a C3-C6 straight chain alkylene group in which one piperazine may be interposed; R<2> indicates a C2-C10 alkyl group, alkenyl group or alkynyl group; a lower alkyl group or lower alkenyl group having a substituent; or a cycloalkyl group which may have a substituent; R<3> indicates the same group as R<1> or -COO-R<4>; and R<4> indicates a lower alkyl group which may have a substituent or its pharmacologically acceptable salt and an anti-allergenic drug, antiphlogistic, drug for overcoming resistance to anti-cancer drugs, or drug for reinforcing the effect of anti-cancer drugs containing the same as effective ingredients.