| 摘要 |
A process for production of L-aspartic acid comprises the steps of (1) contacting (A) an enzyme-containing material having maleate isomerase activity and aspartase activity, or (B) an enzyme-containing material having maleate isomerase activity and an enzyme-containing material having aspartase activity, with a substrate solution containing maleic acid and ammonia, and/or ammonium maleate, to form L-aspartic acid, (2) recovering L-aspartic acid from the reaction solution by adding maleic anhydride and/or maleic acid to the reaction solution to crystallize L-aspartic acid, and (3) recycling the mother liquor from the crystallization as the substrate solution by addition to ammonia. L-Aspartic acid crystals accompanied by a small amount by weight of maleic acid and a salt thereof are obtained as the final product.
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