METHODS FOR ENRICHING TARGET NUCLEIC ACID SEQUENCES
摘要
The invention includes selective amplification methods for enriching target nucleic acid sequences that are present in a first source of nucleic acid but absent from a second source of nucleic acid. These methods involve using phenol to enhance the rate of the hybridization step, as well as modifications for reducing the amounts of reagents required for the reactions. Also included are methods for identifying sequences shared by two or more populations of nucleic acids.
申请公布号
WO9737042(A1)
申请公布日期
1997.10.09
申请号
WO1997US04608
申请日期
1997.03.21
申请人
PATHOGENESIS CORPORATION;PARKER, JAY, D.;SMITH, KIRSTEN, T.;CHALLONER, PETER, B.
发明人
PARKER, JAY, D.;SMITH, KIRSTEN, T.;CHALLONER, PETER, B.