| 发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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| 申请公布号 |
CA2249599(A1) |
申请公布日期 |
1997.10.09 |
| 申请号 |
CA19972249599 |
申请日期 |
1997.03.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
WILLIAMS, THERESA M.;WEI, DONG D. |
| 分类号 |
A61K31/00;A61K31/495;A61K31/496;A61P9/00;A61P13/00;A61P13/12;A61P27/00;A61P27/02;A61P31/00;A61P31/12;A61P35/00;A61P43/00;C07D401/06;C07D403/06;(IPC1-7):C07D403/06;C07D401/04;C07D471/04;C07D495/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;A61K31/55 |
主分类号 |
A61K31/00 |
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