| 发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein tr ansferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogen e protein Ras.
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| 申请公布号 |
CA2250587(A1) |
申请公布日期 |
1997.10.09 |
| 申请号 |
CA19972250587 |
申请日期 |
1997.03.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DINSMORE, CHRISTOPHER J. |
| 分类号 |
A61K31/496;A61P9/00;A61P13/12;A61P25/00;A61P27/02;A61P31/12;A61P35/00;A61P43/00;C07D401/06;C07D403/06;(IPC1-7):C07D403/06;C07D471/04;C07D495/04;C07D401/14;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;A61K31/495;A61K31/535;A61K31/54;A61K31/55 |
主分类号 |
A61K31/496 |
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