| 发明名称 |
PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE |
| 摘要 |
There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R1, R2, R3 and X are as defined in the specification, together with processes for preparing them, compositions containing them and their use as pharmaceuticals. Compounds of formula (I) are indicated inter alia for the treatment of chronic bronchitis.
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| 申请公布号 |
CA2250209(A1) |
申请公布日期 |
1997.10.09 |
| 申请号 |
CA19972250209 |
申请日期 |
1997.03.26 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
JOHNSON, MARTIN REDPATH;FINCH, HARRY;INGLIS, GRAHAM GEORGE ADAM;SMITH, ROBIN ANDREW;DOWLE, MICHAEL DENNIS;MACDONALD, SIMON JOHN FAWCETT;HARRISON, LEE ANDREW;SHAH, PRITOM |
| 分类号 |
A61K;A61K31/00;A61K31/40;A61K31/407;A61K31/41;A61K31/415;A61K31/4164;A61K31/4178;A61K31/44;A61K31/4427;A61K31/4439;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/47;A61K31/472;A61K31/4725;A61K31/495;A61K31/496;A61K31/535;A61K31/5375;A61K31/5377;A61K31/55;A61P1/00;A61P1/02;A61P9/00;A61P9/10;A61P11/00;A61P13/00;A61P13/12;A61P17/00;A61P17/06;A61P29/00;A61P35/00;A61P43/00;C07D;C07D207/14;C07D487/04;(IPC1-7):C07D487/04;C07D207/273 |
主分类号 |
A61K |
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