The present invention discloses Growth Factor HTTER36 polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating cellular growth and differentiation, bone formation and wound healing. Also disclosed are antagonists against such polypeptide and their use as a therapeutic to treat neoplasia and to prevent the formation of extracellular matrix molecules in the liver and lung. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
申请公布号
WO9735870(A1)
申请公布日期
1997.10.02
申请号
WO1996US04085
申请日期
1996.03.26
申请人
HUMAN GENOME SCIENCES, INC.;SOPPET, DANIEL, R.;LI, HAODONG