| 发明名称 |
4-[(THIEN-2-YL)METHYL]IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY |
| 摘要 |
The 4-[(THIEN-2-YL)methyl]-imidazoles of formula (I) wherein R is hydrogen or methyl; X is hydrogen, C1-4alkyl, bromine or chlorine; and Y is hydrogen, C1-4alkyl bromine or chlorine; with the proviso that X and Y are not both simultaneaously hydrogen, have exceptional analgesic activity.
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| 申请公布号 |
WO9735857(A1) |
申请公布日期 |
1997.10.02 |
| 申请号 |
WO1997US04768 |
申请日期 |
1997.03.26 |
| 申请人 |
ORTHO PHARMACEUTICAL CORPORATION |
发明人 |
BOYD, ROBERT, E.;RASMUSSEN, CHRIS, ROYCE;PRESS, JEFFREY, B. |
| 分类号 |
A61K31/00;A61K31/415;A61K31/4164;A61K31/4178;A61P9/00;A61P25/04;A61P43/00;C07D409/06;(IPC1-7):C07D409/06;A61K31/38 |
主分类号 |
A61K31/00 |
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